PICSI (Physiological Intracytoplasmic Sperm Injection) Mexico

Medical Information

IMPROVE. PICSI significantly reduces Pregnancy Loss Rates. Here at LIV Fertility Center in Puerto Vallarta, we implement the best tools for the screening and selection of ICSI to improve success rates considerably.


PICSI is a method of selecting the best possible sperm for fertilization before injection into the egg during IVF.

Sperm are placed in the PICSI dish containing samples of hyaluronan (a naturally occurring biopolymer found in all human cells) hydrogel.

The PICSI procedure assists our embryologist, Emb. Karla Ruiz, to select sperm according to how well they bind to the hyaluronan covering the egg cell. Mature, biochemically competent sperm bind are then isolated by the embryologist and used for ICSI.

PICSI is highly recommended in these particular cases:

  • Previous failure or low fertilization including after ICSI.
  • Low embryo quality or their failure to develop (not related to poor egg quality).
  • Repeated miscarriages.
  • Males with high sperm DNA fragmentation.

PICSI Dish for Sperm Selection

Sperm is added to the dot of hyaluronan and within minutes the bound sperm are attached by their acrosome to the surface of the dot. Selecting an individual bound sperm with enhanced genetic and developmental integrity ensures that the sperm selected is the optimal sperm from the sample.

For sperm with poor binding capability as measured on the HBA slide, a significant decrease in miscarriage rate may result when the PICSI dish is used to identify the bound sperm for PICSI.

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